Our Targets

We’re hard at work in the lab developing proprietary microbes and enzymes to address major global health and sustainability challenges.

Pipeline of product opportunities

Biologically produced L-methionine

We have created bacterial strains for production of L-methionine that is widely used in poultry and swine feed.

Currently all methionine is produced using chemical synthesis, which is toxic, resource intensive and expensive.

We have a solution to this: biologically produced L-methionine.

Function Generator™ is broadly applicable and will enable improvements in numerous microbial species used across multiple industries.

Primordial Genetics is creating bacterial strains for production of L-methionine, an essential amino acid that is widely used in poultry and swine feed. All methionine is currently produced chemically, and its cost-competitive biological production is an unsolved problem. We are using our Function Generator™ platform technology to uncover novel genetic mechanisms contributing to the efficiency of methionine.

Primordial Genetics is developing improved bacterial and yeast strains for commercial protein production as well as protein expression for R&D purposes, including:

  1. Solubility: expression of proteins in soluble form that are otherwise insoluble

  2. Expanded use of E. coli for expression of ‘recalcitrant’ proteins that don’t express well in bacterial hosts and that currently require more expensive production hosts

  3. Efficient protein secretion

  4. Immunoglobulin expression in E. coli including monoclonal antibodies: we are developing multiple traits in E. coli that when combined will allow efficient antibody discovery and production in a bacterial system

Function Generator enables the discovery of novel, active proteins such as new therapeutics, enzymes with improved activity or trait genes for microbes and plants

Primordial Genetics is negotiating collaborations and partnerships with companies in this space to produce tolerance phenotypes for toxic products and productivity increases in biological production systems

Function Generator can spur the development of advanced traits for use in transgenic crop plants, including:

  • Herbicide tolerance

  • Stress tolerance

  • Photosynthetic efficiency and productivity

Function Generator enables the discovery and production of chemicals and pharmaceuticals through genetic optimizations of actinomycete bacteria and other microbial sources of natural products.

Primordial Genetics has established a collaboration with Fermalogic Inc. to pursue large-scale isolation of activated actinomycete strains secreting natural products possessing diverse structures and novel activities. This will be accomplished by developing general genetic solutions for unlocking silent biosynthetic pathways in actinomycete bacteria.

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Bacteria

Fuels
Chemicals
Food and feed ingredients
Therapeutic proteins
Enzymes

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Plants

Food and feed
Structural materials
Fibers
Fuels
Chemical feedstocks

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Yeast & Fungi

Fuels & chemicals
Foods and beverages
Fermentation products
Biochemicals
Proteins & enzymes

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Algae

Carbon remediation
Renewable fuels
Renewable chemicals
Food and feed additives
Water cleanup

Primordial World HQ

3550 General Atomics Court Building 2, Suite 400 San Diego, CA 92121

info@primordialgenetics.com

(858) 366-0770

Pushing the frontiers of Constructive Biology

©2020 Primordial Genetics, Inc.

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